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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原其它S0B2023S-RMab? CD23 Recombinant Rabbit mAb (SDT-028-67)

S-RMab? CD23 Recombinant Rabbit mAb (SDT-028-67)
產(chǎn)品簡介:

S-RMab? CD23 Recombinant Rabbit mAb (SDT-028-67)

產(chǎn)品型號(hào):S0B2023

更新時(shí)間:2025-06-30

廠商性質(zhì):生產(chǎn)廠家

訪問量:36

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產(chǎn)品介紹

CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. CD23 is known to have a role of transportation in antibody feedback regulation. Antigens which enter the blood stream can be captured by antigen specific IgE antibodies. The IgE immune complexes that are formed bind to CD23 molecules on B cells, and are transported to the B cell follicles of the spleen. In flow cytometry, CD23 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell lymphoma (CD23-negative). CD23 can also be demonstrated in germinal centre follicular dendritic cells using immunohistochemistry but is minimally expressed by benign germinal center B cells.

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