PE Mouse Anti-Human CD62P Antibody (S-921-3)

產(chǎn)品型號：S0B5481

更新時間：2025-06-30

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD62P, also known as P-selectin, is a 140 kDa type I transmembrane glycoprotein that plays a crucial role in cell adhesion and immune responses. It is stored in α-granules of platelets and Weibel-Palade bodies of endothelial cells, and is rapidly relocated to the cell surface upon activation by stimuli such as thrombin or histamine. CD62P mediates the initial adhesion and rolling of leukocytes on endothelial cells during inflammation and facilitates interactions between activated platelets and neutrophils or monocytes. It binds to specific carbohydrate ligands on leukocytes in a calcium-dependent manner. Additionally, CD62P is used as a marker for platelet activation and has potential diagnostic value in various diseases.

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